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A Research Centre under MOSTI to oversee and implementing Nanotechnology Agenda for the nation.

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Effects on diameter and morphology of polycaprolactone nanofibers infused with various concentrations of selenium nanoparticles

Electrospinning is one of the techniques used in the fabrication of nanofibers. Polycaprolactone (PCL), is a biodegradable polymer which was commonly electrospun without the presence of nanoparticles as additives and/or filler in the applications such as tissue engineering, biosensors, filtration, wound dressings, drug delivery and enzyme immobilization. In this study, via FESEM analyses, the effects on the diameter and morphology of PCL nanofibers was investigated with respect to various concentration of selenium nanoparticles (SeNP). Increasing the concentration of SeNP from 0.2 to 1.0% (w/v) resulted in increased of fiber diameter as well as the density of the nanofiber networking.
Consequently, the formation of beads have also increased with the increment of the concentration of SeNP. The images from FESEM micrographs showed the formation of “aligned fibers” with the average size of less than 550 nm. The optimized concentration of SeNP obtained was 0.4 % w/v for the formation of aligned fibers with a uniform diameter in size and the least formation of beads in the matrices. Aligned nanofibers are biocompatible and can be used in tissue engineering and wound dressing applications. Meanwhile, nanofibers with beads are suitable for filtration design in water and gaseous applications.

Data and Resources

FieldValue
Contact Name / Contributor
Nurul Asyikin Kamaruzaman
Contact Email
Subject Field of Research MRDCS 6th
Engineering and Technology
Subject Socio Economic Objective MRDCS 6th
Advanced Experimental and Applied Science
Publisher
License
License Not Specified
Public Access Level
Public
Homepage URL
Language
English (United Kingdom)
Modified
2020-04-22
Release Date
2019-11-22
Identifier
8c29eb48-53b2-4775-ae03-9874cf224d41